Herpes Simplex Encephalitis: Lack of Clinical Benefit of Long-term Valacyclovir Therapy
نویسندگان
چکیده
منابع مشابه
Gnann JW et al (Clin Infect Dis 2015; 61:683-91). Herpes Simplex Encephalitis: Lack of Clinical Benefit of Long-term Valacyclovir Therapy.
BACKGROUND Despite the proven efficacy of acyclovir (ACV) therapy, herpes simplex encephalitis (HSE) continues to cause substantial morbidity and mortality. Among patients with HSE treated with ACV, the mortality rate is approximately 14%-19%. Among survivors, 45%-60% have neuropsychological sequelae at 1 year. Thus, improving therapeutic approaches to HSE remains a high priority. METHODS Fol...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2015
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/civ369